- S Club 7
- Sade
- Salif Keita
- Salt N Pepa
- Samantha Fox
- Sandi Thom
- Santana
- Santogold
- Sash!
- Savage Garden
- Scissor Sisters
- Scouting For Girls
- Seal
- Sean Paul
- Seasick Steve
- Semisonic
- Shaft
- Shaggy
- Shakespears Sister
- Shakin Stevens
- Shakira
- Shane McGowan
- Shanks And Bigfoot
- Shapeshifters
- Shara Nelson
- Shayne Ward
- Sheena Easton
- Sheryl Crow
- Shirley Bassey
- Shola Ama
- Simon & Garfunkel
- Simon Rattle
- Simple Minds
- Simply Red
- Sinead O'Connor
- Sinitta
- Siobhan Fahey
- Siouxsie Sioux
- Sir Adrian Boult
- Sir Colin Davis
- Sir Georg Solti
- Sir George Solti
- SisQo
- Skunk Anansie
- Sleepless In Seattle
- Smashing Pumpkins
- Snoop Dogg
- Snow Patrol
- So Solid Crew
- Soft Cell
- Sonia
- Sonique
- Sophie Ellis Bextor
- Soul II Soul
- Space
- Space Jam
- Spacedust
- Spandau Ballet
- Spice Girls
- Spiller
- Spin Doctors
- Star Wars
- Starsailor
- Status Quo
- Stephen Street
- Steps
- Stereo MCs
- Stereophonics
- Steve Levine
- Steve Lillywhite
- Streets
- Stuart Colman
- Suede
- Sugababes
- Supatroopas
- Supergrass
- Survivor
- Sweet Female Attitude
- Swing Out Sister
- SWV
- Steve Lipsom
- Steve Winwood
- Stevie Wonder
- Sting
- Stock
- Stock & Two Smoking
- Stock Aitkin & Waterman
- Stock, Aitkin & Waterman
- Sharleen Spiteri
- Stuart Price
- Stooshe